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What's new with the group! |
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Feng Tian discovered a massive selective sweep on chromosome 10-the largest to date in maize. Studying the genes under this sweep will help us to better understand maize domestication and local adaptation. Peter Bradbury used microarrays to identify and map genome specific markers in wheat, a challenging feat for the hexaploid species with three distinct genomes. The Maize Diversity Group has released the ultimate germplasm resource to date for localizing QTLs! The NAM population (5000 RILs from 25 families) that captures a substantial portion of maize diversity is available at the USDA Maize Stock Center. Markers scores are available at Panzea. Details ... With colleagues from around the US, we have dissected the genetic basis of proVitamin A content in maize. We found that the lycopene epsilon cyclase has natural variation to increase proVitamin A content 3-5 fold. This result could in developing more nutritious maize. Using 454 sequencing with colleagues at CSHL, we have identified SNPs between B73 and Mo17. SNPs are available at Panzea. Happy 200th birthday Darwin! He even had insights on maize! In collaboration with Doreen Ware (CSHL), Jer-Ming Chia (CSHL) and George Grills (Cornell), we (Mike Gore, Rob Elshire, Elhan Ersoz, and Jason Peiffer) are developing a maize HapMap for the 27 founder lines of NAM. SNPs are available for use in designing a public maize SNP array |
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Our lab uses functional genomic approaches to dissect complex traits in maize, biofuel grasses, and grapes. We exploit the natural diversity of these plant genomes to identify the individual nucleotides responsible for complex (quantitative) variation.
Currently, our research focuses on developing germplasm resources for complex trait dissection, using genomics to characterize this diversity, dissect a series of traits (drought tolerance, nitrogen use, basic development, carbon metabolism, vitamin A and E content), and provide software tools for analysis. |
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