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PlantCaduceus (PlantCad)

Learns from All Plants

Improve Yield

Genome Modeling

Discover Genes

PlantCaduceus, abbreviated as PlantCAD, is a DNA language model trained to capture 160 million years of plant genome evolution. Built on the state-of-the-art Mamba architecture, it models diverse plant genomes at single-nucleotide resolution using a masked language modeling objective. By learning patterns of evolutionary conservation and divergence, PlantCAD enables cross-species genome annotation and deleterious mutation prediction. Its versatility makes it a powerful AI tool for both basic plant genomics and applied crop improvement.

For more information on how to get started, please visit our GitHub repository.

Contact Us

Tel: 607-255-1809           

Email: sara.miller@cornell.edu

Address

175 Biotechnology Bldg  

Ithaca, NY 14853-2703  

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