TASSEL (Trait Analysis by aSSociation, Evolution and Linkage) is the long-standing workhorse for GWAS and linkage-disequilibrium analysis of complex traits in large, diverse samples โ GLM/MLM models, the unified mixed model, and data handling for big genotype sets. Downloads, documentation, and source now live on GitHub.

The current standalone release for macOS, Windows, and Linux, plus the command-line pipeline. Older TASSEL 3/4 builds are archived in the same repositories.
User guide, pipeline tutorials (GBS / UNEAK), the GLM & MLM workflows, and the command-line reference โ migrated from the old /tassel/docs PDFs to the project wiki.

Prefer R? rTASSEL wraps the TASSEL association and linkage-disequilibrium engine for reproducible R workflows and pipelines.
Bradbury JG, Zhang Z, Kroon DE, Casstevens TM, Ramdoss Y, Buckler ES (2007). TASSEL: software for association mapping of complex traits in diverse samples. Bioinformatics 23(19):2633โ2635.