Our lab uses functional genomic approaches to dissect complex traits in maize, biofuel grasses, and grapes. We exploit the natural diversity of these plant genomes to identify the individual nucleotides responsible for complex (quantitative) variation.
Currently, our research focuses on developing germplasm resources for complex trait dissection, using genomics to characterize this diversity, dissect a series of traits (drought tolerance, nitrogen use, basic development, carbon metabolism, vitamin A and E content), and provide software tools for analysis. The tools we are developing may also be used as a template system for other genetics research, including research for other crops, animals, and even human genetics.
The Buckler Lab Is Recruiting!
The Buckler Lab at the Institute for Genomic Diversity, Cornell University is beginning two exciting new projects to identify the deleterious mutations in functional domains of the maize and cassava genomes, and then build models to predict performance based on these deleterious polymorphisms. We are looking to hire three researchers with a background in machine learning, bioinformatics of genomic data, and/or statistical genetics. Strong skills in computer programming are necessary. Maize has a long been established as a premier system for studying quantitative and statistical genetics, and our group is now using it as a model for the study of the impact of rare alleles and genetic load in maize. We are creating models that bridge genomics with quantitative genetics. We are asking similar questions in cassava. Cassava is one of the most important crops to subsistence in the world, yet until recently very little genomics was applied to improving the crop. The cassava project is in collaboration with a large genomic-assisted breeding effort to take genomic findings to the field. This project has an exciting potential of furthering basic science and applying it quickly to agriculture for the developing world.
If you are interested, please send your CV and cover letter to Sara Miller at