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Jianbing Yan

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Jianbing Yan PDF Print E-mail

Jianbing Yan is a visiting postdoctoral research associate from International Maize and Wheat Improvement Center (CIMMYT). His research is supported by Generation Challenge Program(To Marilyn Warturton), NSF Plant Genome and USDA-ARS(To Edward Buckler).

Educational background:                

Sept. 1998 – June 2003

Ph. D. in Plant Genetics, Huazhong Agricultural University, Wuhan, China

Sept. 1995 – June 1999

B.Sc. in Biotechnology, Huazhong Agricultural University, Wuhan, China 

Professional positions: 

Oct. 2006 – Present

Postdoctoral research associate, International maize and wheat improvement center (CIMMYT), Mexico and Institute of genomic diversity (IGD), Cornell University, Ithaca, NY, USA

Dec. 2005 – Present

Associate professor, College of Agronomy and biotechnology, China Agricultural University (CAU), Beijing, China

Dec. 2003 – Dec. 2005

Assistant professor, College of Agronomy and biotechnology, China Agricultural University (CAU), Beijing, China 

Present research project: 

Development of informative markers through association mapping in maize to improve drought tolerance in cereals  

Drought and low soil fertility are the major limiting factors for cereal-crop production in developing countries. Association analysis through linkage disequilibrium may be a useful new tool for dissection of drought tolerance and identification of superior alleles. A total of 600 diverse maize lines were selected for evaluation and grown in Mexico in 2004 and 2005 under drought stress conditions. Five thousand samples were harvested each year for three tissues (ear tips, silks & leaves) at two timepoints (0 & 7 days after anthesis) and levels of sucrose, glucose, starch, abscisic acid and ABA-glucose ester were measured. Hybrids were produced by crossing 350 lines selected from the 600 diverse maize lines with the tester line CML312.The hybrids were divided into three maturity groups based on flowering time and are now being evaluated in five locations in China, Kenya, Mexico, Thailand, and Zimbabwe. Yield components and secondary traits of interest will be measured for the hybrids under water stress and well-watered conditions across the five locations for two planting seasons (2006 and 2007). Forty six SSR markers distributed randomly across the gnome have been used to evaluate population structure of the lines. More than 300 candidate genes related to biotic or abiotic stress resistance or with the carbohydrate and ABA pathways that might be associated with drought tolerance were selected for association tests. To date, 60 genes have been sequenced in a panel of 48 highly diverse inbred maize and teosinte lines to develop SNP markers. These and other neutral SNPs will be used to scan the drought association mapping panel using the Illumina® genotyping system. Any positive associations found in this project will provide useful information for drought tolerance breeding in maize and potentially other cereal crops as well. 

Main research projects in CAU:

1. QTL fine mapping and cloning

We have developed a set of near isogenic lines (NILs) in maize by backcross continuously combined molecular maker selection. Several interesting QTL had been mapped and the fine mapping and cloning work are ongoing. One major QTL affecting plant height and several yield traits located on chromosome 1 has been narrowed down within 1 cM. A BC4F2/F3 population with more than 10000 individuals has been developed for fine mapping and cloning the QTL. The candidate gene of another QTL also located on chromosome 1 affected kernel weight has been obtained by using comparative strategy and detail functional analysis is ongoing.  

2. Association analysis of maize Pro-Vitamin A and oil content

Some candidate genes associated with maize oil synthesize and Vitamin A biosynthetic pathway have been selected to perform the LD analysis based on some unique materials including: 1) elite maize inbreds used in commercial breeding program in China; 2) high oil maize inbreds that were selected by the breeders in our center in past two decades

3. The genetic basis of maize heterosis

I and our colleagues have developed an "immortalized F2" (Tang et al, 2006) population based on the F2:3 population developed during the period of my doctorate to study the genetic basis of heterosis. We collaborate with Drs. Zhiwu Zhang and Gael Pressoir in Buckler' s lab now for developing models and methods to analyze the unique dataset.  

Grants in CAU: 

Ø        The start-up funding of China Agricultural University, PI (Fine mapping and candidate gene cloning of a main QTL controlling maize plant height)

Ø        National Natural Science Foundation of China (NNSFC), PI (Fine mapping and cloning of main QTL located on chromosome 1 affecting maize yield and agronomic traits)

Ø        Hi-Tech Research and Development Program of China(863), PI (Cloning and Functional Analysis of a Major QTL Affecting Maize yield)

Ø        National Basic Research Project of China (973), Main attendee (Study the genetic basis of heterosis by the strategy of comparative genomics)

Ø        National Natural Science Foundation of China (NNSFC), Co-PI (The Evaluation of coix in Guangxi province using molecular marker and study of molecular evolution on some important genes)

Ø        Harvest-Plus project of China(International project), Main attendee (Breeding and Extension for Higher Levels of Pro- Vitamin A with Conventional and Molecular Strategy in Maize)  


 1.      Yan JB, Tang H, Huang YQ, Shi YG, Li JS, Zheng YL. QTL Mapping for Developmental Behavior for Plant Height in Maize. Chinese Science Bulletin. 2003, 48(23): 2601-2607

 2.      Yan JB, Tang H, Huang YQ, Shi YG, Zheng YL, Li JS. Genomic analysis of plant height in maize through molecular marker. Agricultural Sciences in China. 2003, 10: 1069-1075

3.      Yan JB, Tang H, Huang YQ, Zheng YL, Li JS. QTL mapping and epistatic analysis for yield and yield components using molecular markers with an elite maize hybrid. Euphytica, 2006, 149: 121-131

4.      Yan JB, Tang H, Huang YQ, Zheng YL, Subhash Chander Li JS. A genome scan for quantitative trait loci affecting yield and yield components both in single- and two-locus levels in maize. Chinese Science Bulletin, 2006, 51(12): 1452-1461

5.      Ju CL, Zhang F, Gao YF, Zhang W, Yan JB, Dai JR, Li JS. Cloneing, chromosome mapping and expression analysis of an R2R3-MYB gene under-expressed in maize hybrid. Mol Biol Rep, 2006, 33(2): 103-110

6.      Yan JB, Tang J H, Meng Y J, Ma X Q, Teng W T, Subhash Chander, Li L, Li J S. Improving QTL mapping resolution using genotypically selected samples—a case study with one RIL population. Acta Genetica Sinica, 2006, 33 (7): 617-624 (in English)

7.      Lu GH, Tang JH, Yan JB, Ma XQ, Li JS, Chen SJ, Ma JC, Liu ZX, E LZ1, Zhang YR, Dai JR. Quantitative trait loci mapping of maize yield and its components under different water treatments at flowering time. Journal of Integrative Plant Biology 2006, 48 (10): 1233−1243

8.      Tang JH, Teng WT, Yan JB, Ma XQ, Meng YJ, Li JS. Genetic analysis of plant height using a set of recombinant inbred line populations in maize. Euphytica, 2007, 155:117–124 doi: 10.1007/s10681-006-9312-3

9.      Tang JH, Ma XQ, Teng WT, Yan JB, Wu WR, Dar JR, Li JS. Detection of quantitative trait loci and heterotic loci for plant height using an immortalized F2 population in maize. Chinese Science Bulletin, 2007, 52(4): 477-483

10. Yan JB, Tang H, Huang YQ, Zheng YL, Li JS. Genetics Analysis of Segregation Distortion of Molecular Markers in Maize F2 Population. Acta Genetica Sinica.2003, 30: 913-918(in Chinese)

11. Tang H, Huang YQ, Yan JB, Tang JH, Liu ZH, Zheng YL, Li JS. Genetic Analysis of Yield Traits in Elite Maize Hybrid—YuYu No.22. Acta Agronomica Sinica. 2004, 30(9): 922-926(in Chinese)

12. Yan JB, Wang Y, Tang H, Huang YQ, Zheng YL, Li JS. Comparative analyses between EST sequences concerning plant height of maize and sequences of rice genome database. Acta Agronomica Sinica. 2004,30(7): 657-667(in Chinese)

13. Yan JB, Tang H, Huang YQ, Li JS, Zheng YL. Comparative analyses of genomic locations for quantitative trait loci to important agronomic traits in maize and rice. Acta Genetica Sinica 2004, 31: 1401-1407(in Chinese)

14. Tang H, Yan JB, Huang YQ, Li JS, Zheng YL. QTL analysis of maize agronomic traits. Acta Genetica Sinica, 2005, 32: 203-209

15. Zheng YP, Subhash C, Yang XH, Zhou JQ, Li JS, Yan JB*. A method for detecting SNP based on PCR technique. Journal of China Agricultural University, 2006, 11(3): 51-55(in Chinese)

16. Yang XH, Yan JB, Zheng YP, Yu JM, Li J S. Review of Association Analysis for Quantitative Traits in Plants. Acta Agronomica Sinica. 2007, 33 (4): 523-530(in Chinese) 


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